Thalassemia minor: report of family with haemoglobin lepore

Hemoglobin Lepore is composed of two normal alpha-globin chains and two delta-beta fusion globin chains that result from non-homologous crossing over of genetic material during meiosis. We report two sisters and their family members with Hb Lepore who have similar haematologic characteristics and clinical severity. A review of the literature and clinical treatment are also given.
Category: Case report
Volume: Vol. 46, No 2, april - june 2002
Authors: V. Krmek, E. Bilić
Reference work: