The possible role of iodinated contrast in enhancing acute kidney injury in a critically ill neonate – a case report

A multi-modality approach is necessary for accurate diagnosis in case of congenital heart diseases  present in the neonatal period. Advances in medical imaging have increased dependence on the information provided by radiological  studies. However, several of these studies require the use of contrast, which may enhance the risk  of contrast-induced acute kidney injury. We report on a case of a neonate with transposition of  great arteries who was submitted to iodinated contrast during angiotomography. Soon after the  procedure, he presented anuria and increased urea and creatinine levels, and was diagnosed with a  contrast-induced acute kidney injury. Despite the use of peritoneal dialysis, he died soon  thereafter. Post mortem analysis showed extensive coagulative necrosis in the renal cortical and  medullary layers.

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