Fulminating Shigella Encephalopathy (ekiri syndrome)

Complications of shigella infection include both intestinal and extraintestinal manifestations. Hemolytic uremic syndrome and central nervous system complications are among the most common extraintestinal manifestations of shigellosis. Neurological manifestation, particularly seizures and encephalopathy, are not common in childhood shigellosis. Brain edema is a common finding in patients presenting with severe shigella encephalopathy. Shiga toxin production is not essential for development of shigella associated neurological symptoms. Early recognition and proper management of cases of severe shigella encephalopathy may help improve the outcome. A case is reported of a 2.5-year-old female child with severe fulminating shigella encephalopathy (ekiri syndrome) who achieved complete recovery. Brain computed tomography findings of this patient are presented.

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